it does, but only in the normal midi controller aspect...notes, clock, cc's all work with mrcc but i cant get reliq to go into "daw" mode through it... i can only achieve that going direct to computer from reliq with nothing else involved... and "daw" basically makes it so you can control all daw aspects from reliq, depending the daw your using but for me it acts like a push for ableton and gives clip launch and scene capture and so on and so on...so, if you want to control plug ins and use it as a clock then yes... but if you want the daw mode aspect i have not been able to make that work....